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1

The nuclear RNase III Drosha initiates microRNA processing

Lee, Yoontae, Ahn, Chiyoung, Han, Jinju, Choi, Hyounjeong, Kim, Jaekwang, Yim, Jeongbin, Lee, Junho, Provost, Patrick, Rådmark, Olof, Kim, Sunyoung

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 480 KB

english, 2003

2

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

Alexander Seiler, Manuela Schneider, Heidi Förster, Stephan Roth, Eva K. Wirth, Carsten Culmsee, Nikolaus Plesnila, Elisabeth Kremmer, Olof Rådmark, Wolfgang Wurst, Georg W. Bornkamm, Ulrich Schweizer

Journal:

Cell Metabolism

Année:

2008

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2008

3

Mutation analysis of the human 5-lipoxygenase C-terminus: Support for a stabilizing C-terminal loop

Hisayo Okamoto, Tove Hammarberg, Ying-Yi Zhang, Bengt Persson, Takashi Watanabe, Bengt Samuelsson, Olof Rådmark

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2005

Langue:

english

Fichier:

PDF, 428 KB

english, 2005

4

Letter to the Editor: NMR structure of human coactosin-like protein

Edvards Liepinsh, Marija Rakonjac, Vincent Boissonneault, Patrick Provost, Bengt Samuelsson, Olof Rådmark, Gottfried Otting

Journal:

Journal of Biomolecular NMR

Année:

2004

Langue:

english

Fichier:

PDF, 389 KB

english, 2004

5

Novel oxylipins formed from docosahexaenoic acid by potato lipoxygenase—10(S)-hydroxydocosahexaenoic acid and 10,20-dihydroxydocosahexaenoic acid

Igor A. Butovich, Mats Hamberg, Olof Rådmark

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 470 KB

english, 2005

6

Recombinant mouse leukotriene A4 hydrolase: a zinc metalloenzyme with dual enzymatic activities

Anders Wetterholm, Juan F. Medina, Olof Rådmark, Robert Shapiro, Jesper Z. Haeggström, Bert L. Vallee, Bengt Samuelsson

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

1991

Langue:

english

Fichier:

PDF, 554 KB

english, 1991

7

Arachidonic acid is a physiological activator of the ryanodine receptor in pancreatic β-cells

Orison O. Woolcott, Amanda J. Gustafsson, Mensur Dzabic, Cristina Pierro, Patrizia Tedeschi, Johanna Sandgren, M. Rizuanul Bari, Nguyen K. Hoa, Marta Bianchi, Marija Rakonjac, Olof Rådmark, Claes-Göra

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 243 KB

english, 2006

8

5-Lipoxygenase: Regulation and possible involvement in atherosclerosis

Olof Rådmark, Bengt Samuelsson

Journal:

Prostaglandins and Other Lipid Mediators

Année:

2007

Langue:

english

Fichier:

PDF, 334 KB

english, 2007

9

5-Lipoxygenase: regulation of expression and enzyme activity

Olof Rådmark, Oliver Werz, Dieter Steinhilber, Bengt Samuelsson

Journal:

Trends in Biochemical Sciences

Année:

2007

Langue:

english

Fichier:

PDF, 782 KB

english, 2007

10

Arachidonate 5-lipoxygenase

Journal:

Prostaglandins and Other Lipid Mediators

Année:

2002

Langue:

english

Fichier:

PDF, 296 KB

english, 2002

11

Calcitriol and transforming growth factor-β upregulate 5-lipoxygenase mRNA expression by increasing gene transcription and mRNA maturation

Damaris Härle, Olof Rådmark, Bengt Samuelsson, Dieter Steinhilber

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 639 KB

english, 1998

12

Leukotriene B4: A highly potent and stereospecific factor stimulating migration of polymorphonuclear leukocytes

CURT L. MALMSTEN, JAN PALMBLAD, ANN-MARIE UDÉN, OLOF RÅDMARK, LARS ENGSTEDT, BENGT SAMUELSSON

Journal:

Acta Physiologica

Année:

1980

Langue:

english

Fichier:

PDF, 249 KB

english, 1980

13

Mechanisms of leukotriene-induced contractions of guinea pig airways: Leukotriene C4 has a potent direct action whereas leukotriene B4 acts indirectly

SVEN-ERIK DAHLÉN, PER HEDQVIST, PÄR WESTLUND, ELISABETH GRANSTRÖM, SVEN HAMMARSTRÖM, JAN ÅKE LINDGREN, OLOF RÅDMARK

Journal:

Acta Physiologica

Année:

1983

Langue:

english

Fichier:

PDF, 790 KB

english, 1983

14

14,15-Dihydroxy-5,8,10,12-eicosatetraenoic : Enzymatic formation from 14,15-leukotriene A4

Anders WETTERHOLM, Jesper HAEGGSTRÖM, Mats HAMBERG, Johan MEIJER, Olof RÅDMARK

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 670 KB

english, 1988

15

Guinea-pig liver leukotriene A4 hydrolase : Purification, characterization and structural properties

Jesper HAEGGSTRÖM, Tomas BERGMAN, Hans JÖRNVALL, Olof RÅDMARK

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 930 KB

english, 1988

16

Human fibroblasts show expression of the leukotriene-A4-hydrolase gene, which is increased after simian-virus-40 transformation

Juan F. MEDINA, Carlos BARRIOS, Colin D. FUNK, Olle LARSSON, Jesper HAEGGSTRÖM, Olof RÅDMARK

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 557 KB

english, 1990

17

Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes

Takashi IZUMI, Olof RÅDMARK, Hans JÖRNVALL, Bengt SAMUELSSON

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 805 KB

english, 1991

18

Molecular cloning of a 12-lipoxygenase cDNA from rat brain

Takashi WATANABE, Juan F. MEDINA, Jesper Z. HAEGGSTRÖM, Olof RÅDMARK, Bengt SAMUELSSON

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 895 KB

english, 1993

19

Mutations at the C-Terminal Isoleucine and Other Potential Iron Ligands of 5-Lipoxygenase

Tove Hammarberg, Ying-Yi Zhang, Birger Lind, Olof Rådmark, Bengt Samuelsson

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 835 KB

english, 1995

20

Molecular Cloning and Functional Characterization of Mouse Coactosin-like Protein

Johanne Doucet, Patrick Provost, Bengt Samuelsson, Olof Rådmark

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 265 KB

english, 2002

21

Leukotriene A4 hydrolase in the human B-lymphocytic cell line Raji: Indications of catalytically divergent forms of the enzyme

Björn Odlander, Hans-Erik Claesson, Tomas Bergman, Olof Rådmark, Hans Jörnvall, Jesper Z. Haeggström

Journal:

Archives of Biochemistry and Biophysics

Année:

1991

Langue:

english

Fichier:

PDF, 1.15 MB

english, 1991

22

Hemoprotein catalysis of leukotriene formation

Olof Rådmark, Takao Shimizu, Frank Fitzpatrick, bengt Samuelsson

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Année:

1984

Langue:

english

Fichier:

PDF, 544 KB

english, 1984

23

Leukotriene A4-hydrolase activity in guinea pig and human liver

Jesper Haeggström, Olof Rådmark, Frank A. Fitzpatrick

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Année:

1985

Langue:

english

Fichier:

PDF, 669 KB

english, 1985

24

Leukotriene A4: metabolism in different rat tissues

Juan F. Medina, Jesper Haeggström, Maria Kumlin, Olof Rådmark

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Année:

1988

Langue:

english

Fichier:

PDF, 843 KB

english, 1988

25

Enzymatic formation of 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid: kinetics of the reaction and stereochemistry of the product

Jesper Haeggström, Anders Wetterholm, Mats Hamberg, Johan Meijer, Robert Zipkin, Olof Rådmark

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Année:

1988

Langue:

english

Fichier:

PDF, 721 KB

english, 1988

26

Enzymatic hydrolysis of leukotriene A4 into 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid and LTB4 by mammalian kidney

Juan F. Medina, Jesper Haeggström, Anders Wetterholm, Alf Wallin, Olof Rådmark

Journal:

Biochemical and Biophysical Research Communications

Année:

1987

Langue:

english

Fichier:

PDF, 616 KB

english, 1987

27

B-lymphocytic cell line Raji expresses the leukotriene A4 hydrolase gene but not the 5-lipoxygenase gene

Juan F. Medina, Björn Odlander, Colin D. Funk, Ji-Yi Fu, Hans-Erik Claesson, Olof Rådmark

Journal:

Biochemical and Biophysical Research Communications

Année:

1989

Langue:

english

Fichier:

PDF, 809 KB

english, 1989

28

Molecular cloning and expression of mouse leukotriene A4 hydrolase cDNA

Juan F. Medina, Olof Rådmark, Colin D. Funk, Jesper Z. Haeggström

Journal:

Biochemical and Biophysical Research Communications

Année:

1991

Langue:

english

Fichier:

PDF, 680 KB

english, 1991

29

The inhibitory effects of BW 755C on arachidonic acid metabolism in human polymorphonuclear leukocytes

Olof Rådmark, Curt Malmsten, Bengt Samuelsson

Journal:

Année:

1980

Langue:

english

Fichier:

PDF, 276 KB

english, 1980

30

Leukotrience C4: isolation from human polymorphonuclear leukocytes

Göran Hansson, Olof Rådmark

Journal:

Année:

1980

Langue:

english

Fichier:

PDF, 374 KB

english, 1980

31

Leukotriene B4 — a stereospecific stimulator for release of lysosomal enzymes from neutrophils

Ingiäld Hafstrom, Jan Palmblad, Curt L. Malmsten, Olof Rådmark, Bengt Samuelsson

Journal:

Année:

1981

Langue:

english

Fichier:

PDF, 387 KB

english, 1981

32

Transformation of 15-hydroperoxy-5,9,11,13-eicosatetraenoic acid into novel leukotrienes

Ulf Lundberg, Olof Rådmark, Curt Malmsten, Bengt Samuelsson

Journal:

Année:

1981

Langue:

english

Fichier:

PDF, 527 KB

english, 1981

33

Effects of novel leukotrienes on neutrophil migration

Jan Palmblad, Ann-Mari Udén, Jan-Åke Lindgren, Olof Rådmark, Göran Hansson, Curt L. Malmsten

Journal:

Année:

1982

Langue:

english

Fichier:

PDF, 365 KB

english, 1982

34

Leukotriene-induced neutrophil aggregation in vitro

Bo Ringertz, Jan Palmblad, Olof Rådmark, Curt Malmsten

Journal:

Année:

1982

Langue:

english

Fichier:

PDF, 307 KB

english, 1982

35

Arachidonate 5-lipoxygenase

Journal:

Journal of Lipid Mediators and Cell Signalling

Année:

1995

Langue:

english

Fichier:

PDF, 1009 KB

english, 1995

36

Human Dicer C-terminus functions as a 5-lipoxygenase binding domain

Vildan Dincbas-Renqvist, Geneviève Pépin, Marija Rakonjac, Isabelle Plante, Dominique L. Ouellet, Andreas Hermansson, Isabelle Goulet, Johanne Doucet, Bengt Samuelsson, Olof Rådmark, Patrick Provost

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Année:

2009

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2009

37

GC-rich sequences in the 5-lipoxygenase gene promoter are required for expression in Mono Mac 6 cells, characterization of a novel Sp1 binding site

David Dishart, Nicole Schnur, Niko Klan, Oliver Werz, Dieter Steinhilber, Bengt Samuelsson, Olof Rådmark

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Année:

2005

Langue:

english

Fichier:

PDF, 453 KB

english, 2005

38

Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site

Bernd L. Sorg, Niko Klan, Sabine Seuter, David Dishart, Olof Rådmark, Andreas Habenicht, Carsten Carlberg, Oliver Werz, Dieter Steinhilber

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Année:

2006

Langue:

english

Fichier:

PDF, 271 KB

english, 2006

39

Functional characterization of vitamin D responding regions in the human 5-Lipoxygenase gene

Sabine Seuter, Sami Väisänen, Olof Rådmark, Carsten Carlberg, Dieter Steinhilber

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

40

The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes

Nicole Schnur, Sabine Seuter, Careen Katryniok, Olof Rådmark, Dieter Steinhilber

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Année:

2007

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2007

41

Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity

Careen Katryniok, Nicole Schnur, Ad Gillis, Andreas von Knethen, Bernd L. Sorg, Leendert Looijenga, Olof Rådmark, Dieter Steinhilber

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Année:

2010

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2010

42

Regulation of 5-lipoxygenase enzyme activity

Olof Rådmark, Bengt Samuelsson

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 219 KB

english, 2005

43

Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis

Olof Rådmark, Bengt Samuelsson

Journal:

Biochemical and Biophysical Research Communications

Année:

2010

Langue:

english

Fichier:

PDF, 413 KB

english, 2010

44

Calcitriol Upregulates Open Chromatin and Elongation Markers at Functional Vitamin D Response Elements in the Distal Part of the 5-Lipoxygenase Gene

Kirsten L. Stoffers, Bernd L. Sorg, Sabine Seuter, Oliver Rau, Olof Rådmark, Dieter Steinhilber

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 970 KB

english, 2010

45

Monocyte-derived soluble protein confers 5-lipoxygenase activity Ca2+-dependent

Eva Bürkert, Olof Rådmark, Dieter Steinhilber, Oliver Werz

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 294 KB

english, 2002

46

A simultaneous quantitation of leukotriene B4 and its ω-oxidized products by gas chromatography-mass spectrometry

Takashi Izumi, Takao Shimizu, Takeshi Kasama, Yousuke Seyama, Hideki Sumimoto, Koichiro Takeshige, Shigeki Minakami, Anders Wetterholm, Olof Rådmark

Journal:

Biochemical and Biophysical Research Communications

Année:

1986

Langue:

english

Fichier:

PDF, 359 KB

english, 1986

47

Leukotriene a: Stereochemistry and enzymatic conversion to leukotriene B

Olof Rådmark, Curt Malmsten, Bengt Samuelsson, David A. Clark, Giichi Goto, Anthony Marfat, E.J. Corey

Journal:

Biochemical and Biophysical Research Communications

Année:

1980

Langue:

english

Fichier:

PDF, 393 KB

english, 1980

48

Leukotriene A4: Enzymatic conversion to leukotriene C4

Olof Rådmark, Curt Malmsten, Bengt Samuelsson

Journal:

Biochemical and Biophysical Research Communications

Année:

1980

Langue:

english

Fichier:

PDF, 469 KB

english, 1980

49

Novel leukotrienes: Products formed by initial oxygenation of arachidonic acid at C-15

William Jubiz, Olof Rådmark, Jan Åke Lindgren, Curt Malmsten, Bengt Samuelsson

Journal:

Biochemical and Biophysical Research Communications

Année:

1981

Langue:

english

Fichier:

PDF, 566 KB

english, 1981

50

Lipidomic Analysis of the Peroxidation Products of Polyunsaturated Fatty Acids and Their Derivatives

Igor A. Butovich, James P. McCulley, Olof Rådmark

Journal:

The Ocular Surface

Année:

2005

Langue:

english

Fichier:

PDF, 143 KB

english, 2005